PERFORMANCE ASSESSMENT OF FOUR CHIMERIC TRYPANOSOMA CRUZI ANTIGENS BASED ON ANTIGEN-ANTIBODY DETECTION FOR DIAGNOSIS OF CHRONIC CHAGAS DISEASE.

Performance Assessment of Four Chimeric Trypanosoma cruzi Antigens Based on Antigen-Antibody Detection for Diagnosis of Chronic Chagas Disease.

The performance of serologic tests in chronic Chagas disease diagnosis largely depends on the type and quality of the antigen preparations that are used for detection of anti-Trypanosoma cruzi antibodies.Whole-cell T.cruzi extracts or recombinant proteins have shown variation in the performance and cross-reactivity.Synthetic chimeric proteins compr

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MCM2 Expression in Different Molecular Subtypes of Epithelial Breast Cancers and its Association with Clinicopathological Parameters and Ki-67 Expression

Introduction: Breast cancer is one of the most common malignancies, with few subtypes having a more aggressive outcome and resistance to conventional therapies, Triple Negative Breast Cancers (TNBCs) being one such variant.The Ki-67 lacks reproducibility and a standardised cut-off.MCM2 (Minichromosome Maintenance 2) has role in DNA repair and repli

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MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A

Introduction: Globally, hepatocellular carcinoma (HCC) is the sixth most common malignancy and it has the fourth highest mortality.MicroRNAs play a significant part in biological processes in cell formation and advancement by targeting genes in many cancers including HCC.Objective: In the present study we examine the involvement of miR-4521 and FAM

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Revisiting knowledge, attitudes and practice (KAP) on human papillomavirus (HPV) vaccination among female university students in Hong Kong

Despite cervical cancer can be preventable by HPV vaccination, little is known on its associated factors among young females in Hong Kong.This study aimed to investigate the present situation regarding the self-reported knowledge, attitudes and practice (KAP) of Human Papillomavirus (HPV) vaccination and to examine their associated factors among fe

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